Scleroderma with Nodular Scleroderma

Scleroderma with Nodular Scleroderma

BACKGROUND Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type. Treatment is challenging, and several treatments modalities have been reported with unsatisfactory results. MAIN OBSERVATIONS We present a case of systemic scleros...

Nodular scleroderma and pleomorphic acid-fast bacteria.

This report describes a rare form of scleroderma associated with multiple, elevated, dermal nodules. In addition, rare acid-fast bacteria, and less rare non-acid-fast coccoid forms were seen in histologic sections from the nodules. Skin culture isolates in thioglycolate broth were positive for both intermittently acid-fast coccobacilli, as well as non-acid-fast cocci compatible with Staphylococ...

When is scleroderma really scleroderma?

Scleroderma.

The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specific autoantibodies are also found in scleroderma, but scleroderma is different from other cutaneous autoimmune diseases because epithelial injury does not occur. Multiple factors and combinations of factors (immune ...

Nodular/keloidal scleroderma: acquired collagenous nodules in systemic sclerosis.